|Portrayed by||Thure Lindhardt|
|First appearance||The Face of Death|
|Latest appearance||The Prince|
Rufio is Catherina Sforza's assassin.
Rufio is a ruthless assassin working under Catherina Sforza, as a student of the art of death. He is sent to Rome by his patron to bring about the Borgias' downfall, and he tries to enlist Cardinal Ascanio Sforza's help in doing so.
|Season three appearances|
|The Face of Death||The Purge||Siblings||The Banquet of Chestnuts||The Wolf and the Lamb|
|Relics||Lucrezia's Gambit||Tears of Blood||The Gunpowder Plot||The Prince|
Every photo of Rufio on this wiki can be seen here.